Concepedia

Enantioselective synthesis of spirooxoindoles via chiral auxiliary (bicyclic lactam) controlled S<sub>N</sub>Ar reactions

Subhabrata Sen, Venkata R. Potti, Ramu Surakanti, Y. L. N. Murthy

Organic & Biomolecular Chemistry · 2010 · 30 citations · 27 references

DOI

Concepts

Abstract

A highly efficient enantioselective S(N)Ar reaction of chiral acyl bicyclic lactam with substituted-2,4-dinitrobenzenes was developed, affording products containing quarternary stereogenic centers. They are further utilized towards an enantioselective synthesis of spirooxoindoles.

References

27

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