Reserpine can confer stress tolerance and lifespan extension in the nematode C. elegans

THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>

Sydney Brenner · Genetics · 1974 · 15.5K citations · Full text

Life Sciences, Biology, Genetics +14

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur, Kevin Pearson, Nathan L. Price et al. · Nature · 2006 · 4.2K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +11

A C. elegans mutant that lives twice as long as wild type

Cynthia Kenyon, Jean Chang, Erin Gensch et al. · Nature · 1993 · 3.4K citations

Life Sciences, Biology, Genetics +6

<i>daf-2</i> , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in <i>Caenorhabditis elegans</i>

Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu et al. · Science · 1997 · 2.3K citations

Life Sciences, Biology, Genetics +17

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

Jason G. Wood, Blanka Rogina, Siva Lavu et al. · Nature · 2004 · 1.9K citations

Life Sciences, Biochemistry, Genetics +16