Concepedia

Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

David Olmos, Sophie Postel‐Vinay, L Rhoda Molife, Scott H. Okuno, Scott M. Schuetze, M. Luisa Paccagnella, Gretchen N. Batzel, Donghua Yin, Kathy Pritchard‐Jones, Ian Judson,

The Lancet Oncology · 2009 · 339 citations · 25 references

DOIFull text

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Concepts

References

25

Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

George D. Demetri, Margaret von Mehren, Charles D. Blanke et al. · New England Journal of Medicine · 2002 · 4.4K citations · Full text

, , +14

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

Susan E. Hankinson, Walter C. Willett, Graham A. Colditz et al. · The Lancet · 1998 · 1.8K citations

, , +8

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

Joan Massagué, Michael Czech · Journal of Biological Chemistry · 1982 · 714 citations · Full text

, , +16

Short-Term Metabolic Effects of Recombinant Human Insulin-like Growth Factor I in Healthy Adults

Hans‐Peter Guler, Jürgen Zapf, E. R. Froesch · New England Journal of Medicine · 1987 · 561 citations

, , +12

Molecular Targeting of Platelet-Derived Growth Factor B by Imatinib Mesylate in a Patient With Metastatic Dermatofibrosarcoma Protuberans

Brian P. Rubin, Scott M. Schuetze, Janet F. Eary et al. · Journal of Clinical Oncology · 2002 · 372 citations

, , +17