Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

R. Michael Snider, Jay W. Constantine, John Lowe et al. · Science · 1991 · 864 citations

Potent Nonpeptide Antagonist, Biochemistry, Functional Selectivity +12

Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome

James Ritchie · Gut · 1973 · 827 citations · Full text

Irritable Colon Syndrome, Functional Gastrointestinal Disorder, Health Sciences +11

Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat

Timothy J. Ness, G. F. Gebhart · Brain Research · 1988 · 661 citations

Functional Gastrointestinal Disorder, Health Sciences, Gastrointestinal Pharmacology +13

Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms ¹

Cinda J. Helke, James E. Krause, Patrick W. Mantyh et al. · The FASEB Journal · 1990 · 441 citations

Electrical Spiking Activity and Propulsion in Small Intestine in Fed and Fasted Rats

M Ruckebusch, Jean Fioramonti · Gastroenterology · 1975 · 274 citations

Physiological Research, Neurophysiology, Neuroanatomy +15