Concepedia

Protease-Activated Receptor-2 Modulates Protease-Activated Receptor-1–Driven Neointimal Hyperplasia

Leila M. Sevigny, Karyn M. Austin, Ping Zhang, Shogo Kasuda, Sheida Sharifi, Lidija Covic, Athan Kuliopulos

Arteriosclerosis Thrombosis and Vascular Biology · 2011 · 70 citations · 35 references

DOIFull text

Open access

Abstract

We conclude that PAR2 regulates the PAR1 hyperplastic response to arterial injury leading to stenosis.

References

35

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Thienkhai Vu, David T. Hung, V I Wheaton et al. · Cell · 1991 · 3K citations

, , +15

PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells

Adrienne Boire, Lidija Covic, Anika Agarwal et al. · Cell · 2005 · 836 citations · Full text

, , +9

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

Eric Camerer, Weitong Huang, Shaun R. Coughlin · Proceedings of the National Academy of Sciences · 2000 · 670 citations · Full text

, , +17

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

Xin Liu, Hong Wu, Michael Byrne et al. · Proceedings of the National Academy of Sciences · 1997 · 597 citations · Full text

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

Nathalie Vergnolle, Nigel W. Bunnett, Keith A. Sharkey et al. · Nature Medicine · 2001 · 468 citations

, , +8