Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members

Psychopharmacology: A generation of progress

Malcolm Lader · Journal of Psychosomatic Research · 1978 · 771 citations

Psychoactive Drug, Psychiatry, Medicine +8

Analysis of reduced forms of biopterin in biological tissues and fluids

Takeshi Fukushima, J. C. Nixon · Analytical Biochemistry · 1980 · 715 citations

Reduced Forms, Biochemistry, Biological Tissues +8

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

Mahmoud Tayeh, Michael A. Marletta · Journal of Biological Chemistry · 1989 · 687 citations · Full text

Metabolic Pathways, Amino Acid Arginine, Biochemistry +13

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1‒AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

T.M. Penning, Michael E. Burczynski, Joseph M. Jez et al. · Biochemical Journal · 2000 · 571 citations · Full text

Reduced Biopterin as a Cofactor in the Generation of Nitrogen Oxides by Murine Macrophages

N S Kwon, Carl Nathan, Dennis J. Stuehr · Journal of Biological Chemistry · 1989 · 570 citations · Full text

Nitric Oxide, Lipid Peroxidation, Immunology +22