Concepedia

Spontaneous intestinal perforation in extremely low birth weight infants: association with indometacin therapy and effects on neurodevelopmental outcomes at 18–22 months corrected age

Rajan Wadhawan, William Oh, Betty R. Vohr, Abhik Das, Edward F. Bell, Abbott Laptook, Seetha Shankaran, Barbara J. Stoll, Michele C. Walsh, Rose Higgins

Archives of Disease in Childhood Fetal & Neonatal · 2012 · 58 citations · 21 references

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Abstract

Indometacin used for IVH prophylaxis and ANS were not associated with the occurrence of SIP in ELBW infants. Indometacin used for treatment of symptomatic PDA was however associated with an increased risk of SIP. ELBW infants with SIP have an increased risk of poor neurodevelopmental outcomes.

References

21

Neurodevelopmental and Functional Outcomes of Extremely Low Birth Weight Infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993–1994

Betty R. Vohr, Linda L. Wright, Anna M. Dusick et al. · PEDIATRICS · 2000 · 1.1K citations

Long-Term Effects of Indomethacin Prophylaxis in Extremely-Low-Birth-Weight Infants

Barbara Schmidt, Peter G. Davis, Diane Moddemann et al. · New England Journal of Medicine · 2001 · 709 citations · Full text

Adverse Effects of Early Dexamethasone Treatment in Extremely-Low-Birth-Weight Infants

Ann R. Stark, Waldemar A. Carlo, Jon E. Tyson et al. · New England Journal of Medicine · 2001 · 484 citations · Full text

Prophylaxis of Early Adrenal Insufficiency to Prevent Bronchopulmonary Dysplasia: A Multicenter Trial

Kristi L. Watterberg, Jeffrey S. Gerdes, Cynthia H. Cole et al. · PEDIATRICS · 2004 · 429 citations

Necrotizing Enterocolitis Among Neonates in the United States

Scott O. Guthrie, Phillip V. Gordon, Victor J. Thomas et al. · Journal of Perinatology · 2003 · 388 citations · Full text

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