Long-Term Effects of Indomethacin Prophylaxis in Extremely-Low-Birth-Weight Infants

Abstract

In extremely-low-birth-weight infants, prophylaxis with indomethacin does not improve the rate of survival without neurosensory impairment at 18 months, despite the fact that it reduces the frequency of patent ductus arteriosus and severe periventricular and intraventricular hemorrhage.