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Kinetic Analysis of the Activation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Heterologously Expressed Human P450 Enzymes and the Effect of P450- Specific Chemical Inhibitors on This Activation in Human Liver Microsomes

Human P450 EnzymesMolecular PharmacologyBiochemistryMedicineHepatotoxicityHuman Liver MicrosomesKinetic AnalysisExperimental ToxicologyPharmacologyToxicological MechanismDrug DiscoveryCarbonyl Metabolism