Concepedia

ITI-007 demonstrates brain occupancy at serotonin 5-HT2A and dopamine D2 receptors and serotonin transporters using positron emission tomography in healthy volunteers

Robert E. Davis, Kimberly E. Vanover, Yun Zhou, James Robert Brašić, Maria Guevara, Blanca Bisuna, Weiguo Ye, Vanessa Raymont, William D. Willis, Anil Kumar,

Psychopharmacology · 2015 · 43 citations · 48 references

DOI

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References

48

Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine

Lars Farde · Archives of General Psychiatry · 1992 · 1.4K citations

, , +15

Relationship Between Dopamine D<sub>2</sub> Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia

Shitij Kapur, Robert B. Zipursky, Corey Jones et al. · American Journal of Psychiatry · 2000 · 1.1K citations

, , +17

Synthesis and Evaluation of <sup>11</sup>C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents

Chester A. Mathis, Yanming Wang, Daniel P. Holt et al. · Journal of Medicinal Chemistry · 2003 · 983 citations · Full text

, , +8

The dopamine hypothesis of schizophrenia: focus on the dopamine receptor

American Journal of Psychiatry · 1976 · 555 citations

, , +17

Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients

Anna Nordström, Lars Farde, Frits‐Axel Wiesel et al. · Biological Psychiatry · 1993 · 530 citations

, , +17