O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Accelerate Atherosclerosis in Diabetic ApoE-Null Mice - Concepedia

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O-Glycosylation Regulates Ubiquitination and Degradation of the Anti-Inflammatory Protein A20 to Accelerate Atherosclerosis in Diabetic ApoE-Null Mice

DOI Full Paper Access

80

Citations

47

References

2010

Year

Gautam Shrikhande, Salvatore T. Scali, Cleide G. da Silva, Scott M. Damrauer, Eva Csizmadia, Prabhakar Putheti, Michaela Matthey, Roy Arjoon, Rakesh Patel, Jeffrey J. Siracuse,

Abstract

High glucose/hyperglycemia regulate vascular A20 expression via O-GlcNAcylation-dependent ubiquitination and proteasomal degradation. This could be key to the pathogenesis of accelerated atherosclerosis in diabetes.

References

	Year	Citations

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