Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data

TLDR

High‑throughput sequencing technologies have made low‑cost sequencing of large numbers of samples commonplace, and the variety of sequencing experiments has expanded to include genome re‑sequencing, population‑scale variation detection, whole transcriptome sequencing, and genome‑wide analysis of protein‑bound nucleic acids. We present Artemis as a tool for integrated visualization and computational analysis of different types of HTS datasets in the context of a reference genome and its corresponding annotation. Artemis enables integrated visualization and computational analysis of diverse HTS datasets. Artemis is freely available under a GPL licence for MacOSX, UNIX, and Windows at http://www.sanger.ac.uk/resources/software/artemis/ and can be contacted at [e-mail] or [e-mail].

Abstract

Abstract Motivation: High-throughput sequencing (HTS) technologies have made low-cost sequencing of large numbers of samples commonplace. An explosion in the type, not just number, of sequencing experiments has also taken place including genome re-sequencing, population-scale variation detection, whole transcriptome sequencing and genome-wide analysis of protein-bound nucleic acids. Results: We present Artemis as a tool for integrated visualization and computational analysis of different types of HTS datasets in the context of a reference genome and its corresponding annotation. Availability: Artemis is freely available (under a GPL licence) for download (for MacOSX, UNIX and Windows) at the Wellcome Trust Sanger Institute websites: http://www.sanger.ac.uk/resources/software/artemis/. Contact: [e-mail]; [e-mail]