Anaphylactic transfusion reactions in haptoglobin‐deficient patients with IgE and IgG haptoglobin antibodies

Abstract

Anaphylactic NHTRs in these patients with haptoglobin deficiency associated with serum haptoglobin antibodies were suggested to be prevalent in Japan. In addition to IgG antibodies, IgE haptoglobin antibodies detected in the sera of such patients were suggested to play a role in the occurrence of the reactions.