Primary Cerebral Hemangiosarcoma in a 6-Week-Old Dog

Abstract

A primary cerebral hemangiosarcoma was identified in a 6-week-old, female, cross-breed dog. Grossly, the tumor mass was poorly demarcated from the adjacent neuropil, hemorrhagic, and caused effacement of the right dorsolateral cerebral hemisphere. Microscopically, the tumor was composed of an infiltrative mass of small vascular channels lined by neoplastic endothelial cells that stained variably with factor VIII-related antigen and negatively with glial fibrillary acidic protein. This is the first description of a primary intracranial hemangiosarcoma in an immature dog.