Concepedia

Autoantibodies in Patients with Chronic Obstructive Pulmonary Disease

Carol Feghali‐Bostwick, Aneal S. Gadgil, Leo E. Otterbein, Joseph M. Pilewski, Michael W. Stoner, Eva Csizmadia, Yingze Zhang, Frank C. Sciurba, Steven R. Duncan

American Journal of Respiratory and Critical Care Medicine · 2007 · 266 citations · 33 references

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Abstract

IgG autoantibodies with avidity for pulmonary epithelium, and the potential to mediate cytotoxicity, are prevalent in patients with COPD. Autoreactive adaptive immune responses may be important in the etiology of this disease.

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Seung‐Hyo Lee, Sangeeta Goswami, Ariel Grudo et al. · Nature Medicine · 2007 · 584 citations · Full text

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