Hypoglycaemic and Antihyperlipidemic Effects of Henna Leaves Extract (Lawsonia inermis Linn) on Alloxan Induced Diabetic Mice

Abstract

This is a study of the effect of Inai (Lawsonia inermis Linn) leaves extract on glucose, total cholesterol and triglyceride of the blood of mice which was induced by alloxan of 70 mg/kgBW. Inai leaves extract was obtained by the percolation of dried inai leaves using 70% ethanol. Sample treatments were done at the 0, 3 rd 7 th days and 14 th days after the mice had underwent the hyperglycaemic condition. The results showed that the feeding of 0.8 g/kgBW of inai extract decreased the glucose concentration from 194 mg/dl to normal condition after the 14 th day. A similar result was noticed on total cholesterol concentration as the total cholesterol concentration decreased from 148.9 mg/dl to 55.3 mg/dl, while triglyceride concentration decreased from 225.7 mg/dl to 76.9