Genetic Analysis of Rwandan Patients With Cystic Fibrosis-Like Symptoms

Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping

Johanna M. Rommens, Michael C. Iannuzzi, Bat-Sheva Kerem et al. · Science · 1989 · 3.2K citations

Life Sciences, Genetics, Molecular Genetics +11

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

Richard A. Shimkets, David G. Warnock, Christopher M. Bositis et al. · Cell · 1994 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +15

CFTR as a cAMP-Dependent Regulator of Sodium Channels

M. Jackson Stutts, Cecilia M. Canessa, John C. Olsen et al. · Science · 1995 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +17

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

Marcus Mall, Barbara R. Grubb, Jack R. Harkema et al. · Nature Medicine · 2004 · 899 citations

Veterinary Medicine, Cell Biology, Pathobiology +12

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

Su'e Chang, Stefan Gründer, Aaron Hanukoglu et al. · Nature Genetics · 1996 · 814 citations

Medicine, Molecular Genetics, Physiology +15