Cascade Carbonylation Methods Leading to β‐Diketones and β‐Functionalized δ‐Diketones

Abstract

A radical combination: An intermolecular cascade reaction involving alkyl halides, CO, electron-deficient alkenes, and stannyl enolates proceeds smoothly by a radical chain pathway to give four-component coupling products in good to high yields (see scheme). A series of 1,5-diketones with a substituent at the 3-position was prepared by this method. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z53702_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.