Exposure to a farm environment is associated with <scp>T</scp> helper 1 and regulatory cytokines at age 4.5 years

Abstract

Farming lifestyle seemed to be associated with increased spontaneous production of Th1 and regulatory cytokines. Decreased TNF responses to short-term LPS stimulation in farm-exposed children may imply tolerogenic immune mechanisms. These novel findings might contribute to the asthma and allergy protection in farm environment.