Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia

Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy

Andreas Hochhaus, Sebastian Kreil, A. Corbin et al. · Leukemia · 2002 · 905 citations

Medicine, Molecular Biology, Molecular Genetics +11

High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome–positive chronic phase chronic myeloid leukemia

Hagop M. Kantarjian, Moshe Talpaz, Susan O’Brien et al. · Blood · 2003 · 391 citations · Full text

Medicine, Hematology, Pharmacotherapy +8

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage

Zhi-Min Yuan, Yinyin Huang, Young E. Whang et al. · Nature · 1996 · 224 citations

Life Sciences, Cell Biology, Molecular Biology +13

A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

Ajeeta B. Dash, Ifor R. Williams, Jeffery L. Kutok et al. · Proceedings of the National Academy of Sciences · 2002 · 211 citations · Full text

Medicine, Hematology, Oncology +16

The inv(11)(p15q22) Chromosome Translocation of De Novo and Therapy-Related Myeloid Malignancies Results in Fusion of the Nucleoporin Gene, NUP98, With the Putative RNA Helicase Gene, DDX10

Yasuhito Arai, Fumie Hosoda, Hirofumi Kobayashi et al. · Blood · 1997 · 176 citations · Full text

Life Sciences, Molecular Genetics, Oncology +12