Basic Fibroblast Growth Factor Increases Regional Cerebral Blood Flow and Reduces Infarct Size After Experimental Ischemia in a Rat Model

Abstract

The present study suggested that intracarotid administration of bFGF (100 ng) can reduce infarct size after MCA occlusion. It was speculated that the increased CBF in the penumbral areas of MCA may contribute to contraction of infarct size.