Cell stem cell · 2009 · 61 citations · 11 references
Life SciencesBiologyCell BiologyBioethicsGametogenesisStem Cell BiologyEmbryonic Stem CellsGamete BiologyGamete FormationPluripotent Stem CellsStem Cell DifferentiationStem Cell EthicsAccess To Stem Cell TherapiesEmbryonic Stem Cell BiologyEmbryonic Stem Cell Research EthicsHuman Embryonic Stem CellsInduced Pluripotent Stem Cell EthicsInduced Pluripotent Stem CellsPluripotent Stem Cell DifferentiationStem Cell Sourcing Ethics
An emerging body of data suggests that pluripotent stem cells may be able to differentiate to form eggs and sperm. We discuss the state of the science and the potential social implications and offer recommendations for addressing some of the ethical and policy issues that would be raised by the availability of stem cell-derived gametes.
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Derivation of Oocytes from Mouse Embryonic Stem Cells
Karin Hübner, Guy Fuhrmann, Lane K. Christenson et al. · Science · 2003 · 1.1K citations
Derivation of embryonic germ cells and male gametes from embryonic stem cells
Niels Geijsen, Melissa Horoschak, Kitai Kim et al. · Nature · 2003 · 863 citations