Patient Safety in Surgery · 2010 · 98 citations · 33 references
MedicinePerioperative MedicineSurgeryGeneral SurgeryPatient SafetyPerioperative SafetyAntibiotic ProphylaxisAntimicrobial ProphylaxisPostoperative Infection PreventionProphylactic Antimicrobial UseSurgical ProphylaxisSurgical SafetyAntibiotic Prophylaxis AdministrationAntibiotic Prophylaxis In SurgeryChecklist EffectivenessPostoperative ProphylaxisProphylaxis In Gastrointestinal SurgerySurgical Prophylaxis DurationSurgical Site Infection ProphylaxisTiming Of Prophylactic Antibiotics
BACKGROUND: Surgical site infection (SSI) is an adverse event in which a close relation between process of care and outcome has been demonstrated: administration of antibiotic prophylaxis decreases the risk of SSI. In our tertiary referral centre, a SURgical PAtient Safety System (SURPASS) checklist was developed and implemented. This multidisciplinary checklist covers the entire surgical pathway and includes, among other items, administration of antibiotic prophylaxis before induction of anaesthesia. The aim of this study was to determine the effect of SURPASS implementation on timing of antibiotic prophylaxis. METHODS: A retrospective analysis was performed on two cohorts of patients: one cohort of surgical patients that underwent surgery before implementation of the checklist and a comparable cohort after implementation. The interval between administration of antibiotic prophylaxis and incision was compared between the two cohorts. RESULTS: A total of 772 surgical procedures were included. More than half of procedures were gastro-intestinal; others were vascular, trauma and hernia repair procedures. After implementation, the checklist was used in 81.4% of procedures. The interval between administration of antibiotic prophylaxis and incision increased from 23.9 minutes before implementation of SURPASS to 29.9 minutes after implementation (p = 0.047). In procedures where the checklist was used, the interval increased to 32.9 minutes (p = 0.004). The proportion of patients that did not receive antibiotics until after the incision decreased significantly. CONCLUSION: The use of the SURPASS checklist leads to better compliance with regard to the timing of antibiotic prophylaxis administration.
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Guideline for Prevention of Surgical Site Infection, 1999
Alicia J. Mangram, Teresa Horan, Michele L. Pearson et al. · American Journal of Infection Control · 1999 · 2.9K citations
Medicine, Microbiology, Surgery +17
Alicia J. Mangram, Teresa Horan, Michele L. Pearson et al. · PubMed · 1999 · 2.8K citations
Medicine, Infectious Disease Control, Preventive Medicine +14