Journal of Analytical Toxicology · 1982 · 36 citations · 5 references
MedicineNephrologyToxicologyDialysisHeavy Metal PoisoningHemodialysisHeavy Metal ContaminationMercury PoisoningMercury ToxicologyMetal ToxicityAcute Mercury PoisoningBlood Heavy Metal LevelsContinuous HemodialysisMercury Exposure AssessmentMercury Poisoning ManagementMercury Poisoning TreatmentPenicillamine TherapyUrine Heavy Metal Levels
Mercuric chloride was accidentally ingested by a nineteen-month old boy. He exhibited severe symptoms of inorganic mercury poisoning including acute renal failure. The blood mercury level at the time of admission to hospital was 1920 ng/mL. Following emergency hemodialysis, BAL (2, 3-dimercaptopropanol) therapy and penicillamine treatment, blood levels fell to 500 ng Hg/mL and urine production restarted six days after exposure. Urine mercury reached a high of 2349 ng/mL but rapidly decreased to less than 100 ng/mL within eight days after resumption of voiding. The patient was discharged from hospital a month after admission and follow-up examinations have indicated no permanent renal damage. Blood, hair, and urine samples collected 19 months after the exposure showed normal mercury levels (blood, 6 ng Hg/mL; urine, 7 ng Hg/mL; and hair 500-900 ng Hg/g).
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