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The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)

Prakash G. Jagtap, Garry J. Southan, Erkan Baloglu, Siya Ram, Jon G. Mabley, Anita Marton, Andrew L. Salzman, Csaba Szabó

Bioorganic & Medicinal Chemistry Letters · 2003 · 75 citations · 7 references

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7

Novel inhibitors of poly(ADP-ribose) synthetase

Michael R. Purnell, WILLIAM J. D. WHISH · Biochemical Journal · 1980 · 529 citations · Full text

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Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase.

Marek Banasik, Hajime Komura, Makoto Shimoyama et al. · Journal of Biological Chemistry · 1992 · 479 citations · Full text

, , +13

Facile Preparation of Nucleoside-5‘-carboxylic Acids

Jeffrey B. Epp, Theodore S. Widlanski · The Journal of Organic Chemistry · 1998 · 347 citations

, , +10

Purines inhibit poly(ADP‐ribose) polymerase activation and modulate oxidant‐induced cell death

László Virág, Csaba Szabó · The FASEB Journal · 2001 · 130 citations · Full text

, , +13

Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking of Ligands and Quantitative Structure−Activity Relationship Analysis

Gabriele Costantino, Antonio Macchiarulo, Emidio Camaioni et al. · Journal of Medicinal Chemistry · 2001 · 93 citations · Full text

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