Hepatitis C viral complexity detected by single-strand conformation polymorphism and response to interferon therapy

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Masato Orita, Hiroyuki Iwahana, Hiroshi Kanazawa et al. · Proceedings of the National Academy of Sciences · 1989 · 3.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

Gary L. Davis, Luis A. Balart, Eugene R. Schiff et al. · New England Journal of Medicine · 1989 · 1.7K citations

Pharmacy, Internal Medicine, Pharmacotherapy +14

Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources

Hiroaki Okamoto, Yuichi Sugiyama, S Okada et al. · Journal of General Virology · 1992 · 1.3K citations

Life Sciences, Infectious Diseases, Microbiology +13

Recombinant Interferon Alfa Therapy for Chronic Hepatitis C

Adrian M. Di Bisceglie, Paul Martin, Chris Kassianides et al. · New England Journal of Medicine · 1989 · 1.2K citations

Medicine, Internal Medicine, Pharmacotherapy +17