Clinical features of cytotoxic CD8+ T‐lymphocyte deficiency in chronic rhinosinusitis patients: a demographic and functional study

Abstract

Low CD8+ levels are often identified in CRS patients; however, these patients have disease remarkably similar to those with conventional CRS. This suggests that immune deficiency, whether systemic or locally mediated, is well tolerated and may be present in other forms in CRS. CRS patients with low CD8+ levels may possibly require antibacterial therapies as part of ongoing management.