The <i>ygaVP</i> Genes of <i>Escherichia coli</i> Form a Tributyltin-Inducible Operon

Hervé Gueuné, Marie-José Durand, Gérald Thouand, Michael S. DuBow

Applied and Environmental Microbiology · 2008 · 27 citations · 15 references

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Abstract

A tributyltin (TBT) luxAB transcriptional fusion in Escherichia coli revealed that a TBT-activated promoter is located upstream of two cotranscribed orphan genes, ygaV and ygaP. We demonstrate that transcription from the promoter upstream of ygaVP is constitutive in a ygaVP mutant, suggesting that YgaV is an autoregulated, TBT-inducible repressor.

References

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