Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

John Antoniou, Thomas Steffen, Fred R.T. Nelson et al. · Journal of Clinical Investigation · 1996 · 1K citations · Full text

Medicine, Pathology, Cellular Pathology +7

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration

Christine L. Le Maitre, Anthony J. Freemont, Judith A. Hoyland · Arthritis Research & Therapy · 2005 · 808 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile

Christine L. Le Maitre, Judith A. Hoyland, Anthony J. Freemont · Arthritis Research & Therapy · 2007 · 586 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Nutrition of the Intervertebral Disc: Solute Transport and Metabolism

Søren Holm, Alice Maroudas, J Urban et al. · Connective Tissue Research · 1981 · 537 citations

Life Sciences, Physiology, Veterinary Physiology +17

Matrix Metalloproteinases And Aggrecanase

Sally Roberts, Bruce Caterson, J. Menage et al. · Spine · 2000 · 504 citations

Medicine, Pathobiology, Pathology +17