Concepedia

Utility of Long-Term Cultured Human Hepatocytes as an in Vitro Model for Cytochrome P450 Induction

Georgina Meneses‐Lorente, Christine Pattison, Claire Guyomard, Christophe Chesné, R.P. Heavens, Alan P. Watt, Bindi Sohal

Drug Metabolism and Disposition · 2006 · 21 citations · 26 references

DOI

Concepts

References

26

Long‐Term in Vitro Function of Adult Hepatocytes in a Collagen Sandwich Configuration

James Dunn, Ronald G. Tompkins, Martin L. Yarmush · Biotechnology Progress · 1991 · 703 citations

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Humanized xenobiotic response in mice expressing nuclear receptor SXR

Wen Xie, Joyce L. Barwick, Michael Downes et al. · Nature · 2000 · 657 citations

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Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Thomas Lang, Kathrin Klein, Joachim E. Fischer et al. · Pharmacogenetics · 2001 · 569 citations

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Regulation of the Human CYP2B6 Gene by the Nuclear Pregnane X Receptor

Bryan Goodwin, Linda B. Moore, Catherine M. Stoltz et al. · Molecular Pharmacology · 2001 · 370 citations

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Maintenance of differentiated rat hepatocytes in primary culture.

Harriet C. Isom, T. E. Secott, Ingo Georgoff et al. · Proceedings of the National Academy of Sciences · 1985 · 358 citations · Full text

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