Concepedia

Interferon Regulatory Factor 1 (IRF-1) induces p21WAF1/CIP1 dependent cell cycle arrest and p21WAF1/CIP1 independent modulation of survivin in cancer cells

Michaele J. Armstrong, Michael T. Stang, Ye Liu, Jinbo Gao, Bao‐Guo Ren, Brian S. Zuckerbraun, Raja S. Mahidhara, Quanhua Xing, Eva Pizzoferrato, John H. Yim

Cancer Letters · 2011 · 39 citations · 67 references

DOI

Concepts

References

67

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

Ingo Tamm, Yi Wang, Edward A. Sausville et al. · PubMed · 1998 · 1.3K citations

, , +17

Inhibition of cyclin-dependent kinases by p21.

J. Wade Harper, Stephen J. Elledge, Khandan Keyomarsi et al. · Molecular Biology of the Cell · 1995 · 1K citations · Full text

, , +13

Effects of p21 <sup>Cip1/Waf1</sup> at Both the G <sub>1</sub> /S and the G <sub>2</sub> /M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

Alexander B. Niculescu, Xinbin Chen, Monique Smeets et al. · Molecular and Cellular Biology · 1998 · 726 citations · Full text

, , +17