Susceptibility of cancer cells to β-lapachone is enhanced by ionizing radiation

NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity

John J. Pink, Sarah M. Planchon, Colleen Tagliarino et al. · Journal of Biological Chemistry · 2000 · 366 citations · Full text

Reductase Enzyme Expression Across the National Cancer Institute Tumor Cell Line Panel: Correlation With Sensitivity to Mitomycin C and EO9

Sara A. Fitzsimmons, Paul Workman, Michael R. Grever et al. · JNCI Journal of the National Cancer Institute · 1996 · 234 citations · Full text

Selective killing of cancer cells by β-lapachone: Direct checkpoint activation as a strategy against cancer

Youzhi Li, Xiangao Sun, J. Thomas LaMont et al. · Proceedings of the National Academy of Sciences · 2003 · 228 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +17

Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.

Sarah M. Planchon, Shelly M. Wuerzberger, Benjamín Frydman et al. · PubMed · 1995 · 205 citations · Full text

Chemoprevention Strategy, Apoptosis, Cell Death +18

High levels of expression of the NAD(P)H:Quinone oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin

Thierry Cresteil, Anil K. Jaiswal · Biochemical Pharmacology · 1991 · 201 citations

Reductive Stress, Same Origin, Aldo-keto Reductase +11