Molecular mechanisms in tumor-cell killing by activated macrophages

Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering.

Carl Nathan, Richard K. Root · The Journal of Experimental Medicine · 1977 · 485 citations · Full text

Immunotoxicology, Lipid Peroxidation, Immunology +20

Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide.

Carl Nathan, L H Brukner, S C Silverstein et al. · The Journal of Experimental Medicine · 1979 · 421 citations · Full text

Immunology, Cell Death, Pathology +22

Purification and physico-chemical characterization of rabbit tumor necrosis factor.

Michael R. Ruff, George E. Gifford · The Journal of Immunology · 1980 · 387 citations · Full text

Immunology, Rabbit Tnf, Pathology +17

Activated macrophages kill tumour cells by releasing arginase

G A Currie · Nature · 1978 · 301 citations

Inflammation, Cytokine, Immunology +9

Heterocytolysis by Macrophages Activated by Bacillus Calmette-Gurin: Lysosome Exocytosis into Tumor Cells

John B. Hibbs · Science · 1974 · 272 citations

Immunology, Cell Death, Tumor Cells +24