RSC Advances · 2014 · 14 citations · 12 references
Life SciencesBiochemistryBiotechnologyBioorthogonal ChemistryPost-translational ModificationProtein EngineeringBiocatalytic GlycosylationGlycan AnalysisGlycan LabelingGlycosylation PathwaysProtein GlycoengineeringProtein GlycosylationAzide FunctionalizationGlycan EngineeringPegylationProtein PegylationSite-specific Glycosylation
Primary arylamines were demonstrated to site-specifically incorporate bioorthogonal azide functionality, glycans for glyco-engineering, and PEG chains for PEGylation to protein <italic>via</italic> tyrosine-targeted modification.
12
Enhancement of therapeutic protein in vivo activities through glycoengineering
Steve Elliott, Tony Lorenzini, Sheilah Asher et al. · Nature Biotechnology · 2003 · 516 citations
Dual-Surface Modification of the Tobacco Mosaic Virus
Tara L. Schlick, Zhebo Ding, Ernest W. Kovacs et al. · Journal of the American Chemical Society · 2005 · 512 citations