Concepedia

Long-term outcome of maintenance infliximab therapy in children with Crohnʼs disease

Jeffrey S. Hyams, Trudy Lerer, Anne M. Griffiths, Marian Pfefferkorn, Subra Kugathasan, Jonathan Evans, Anthony Otley, Ryan Carvalho, David Mack, Athos Bousvaros,

Inflammatory Bowel Diseases · 2008 · 181 citations · 23 references

DOIFull text

Open access

Abstract

Infliximab maintenance therapy was a durable and effective treatment that was associated with prolonged corticosteroid withdrawal over a 3-year period in children with CD.

References

23

Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

Stephen B. Hanauer, Brian G. Feagan, Gary R. Lichtenstein et al. · The Lancet · 2002 · 4.1K citations

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A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

Stephan R. Targan, Stephen B. Hanauer, Sander J. H. van Deventer et al. · New England Journal of Medicine · 1997 · 3.1K citations · Full text

Adalimumab for Maintenance of Clinical Response and Remission in Patients With Crohn’s Disease: The CHARM Trial

Jean–Frédéric Colombel, William J. Sandborn, Paul Rutgeerts et al. · Gastroenterology · 2006 · 2.2K citations

, , +7

Infliximab Maintenance Therapy for Fistulizing Crohn's Disease

Bruce E. Sands, Frank Anderson, Çharles N. Bernstein et al. · New England Journal of Medicine · 2004 · 2.2K citations · Full text

Development and Validation of a Pediatric Crohnʼs Disease Activity Index

Jeffrey S. Hyams, George D. Ferry, Francine S. Mandel et al. · Journal of Pediatric Gastroenterology and Nutrition · 1991 · 964 citations