Concepedia

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid and Related Compounds Inhibit Growth of Colon Cancer Cells through Peroxisome Proliferator-Activated Receptor γ-Dependent and -Independent Pathways

Sudhakar Chintharlapalli, Sabitha Papineni, Marina Konopleva, Michael Andreef, Ismael Samudio, Stephen Safe

Molecular Pharmacology · 2005 · 83 citations · 38 references

DOI

Concepts

References

38

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

Béatrice Desvergne · Endocrine Reviews · 1999 · 1.3K citations

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Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.

Min-Nung Huang, Chi‐Tang Ho, Zhi Yuan Wang et al. · PubMed · 1994 · 553 citations

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Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages.

Nanjoo Suh, Tadashi Honda, Heather J. Finlay et al. · PubMed · 1998 · 326 citations

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A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.

Nanjoo Suh, Yongping Wang, Tadashi Honda et al. · PubMed · 1999 · 283 citations

, , +14

Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity.

Florent C. Bender, Marc A. Reymond, Claude Bron et al. · PubMed · 2000 · 280 citations · Full text

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