MIGRATION OF DENDRITIC CELLS TO THE DRAINING LYMPH NODE AFTER ALLOGENEIC OR CONGENEIC RAT SKIN TRANSPLANTATION1

Abstract

The presence of donor-derived DC in the graft draining lymph nodes underlines the importance of the direct route of allo-activation. The lower numbers of migrated His 41+ DC in lymph nodes of allogeneic recipients may be the result of killing of the cells after presentation of the allo-antigens to the recipient T cells.