How we drifted into peptide chemistry and where we have arrived at

β-Peptides: a surprise at every turn

Dieter Seebàch, J. L. Matthews · Chemical Communications · 1997 · 771 citations

Stable Helices, β-Amino Acids, Biochemistry +13

β‐Peptides: Synthesis by <i>Arndt‐Eistert</i> homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin

Dieter Seebàch, Mark Overhand, Florian N. M. Kühnle et al. · Helvetica Chimica Acta · 1996 · 716 citations

Peptide Engineering, Molecular Biology, Peptide Science +16

Umpolung of the Reactivity of Carbonyl Compounds Through Sulfur-Containing Reagents

Bengt‐Thomas Gröbel, Dieter Seebàch · Synthesis · 1977 · 697 citations

Carbonyl Compounds, Chemical Engineering, Engineering +14

β-Peptide Foldamers:  Robust Helix Formation in a New Family of β-Amino Acid Oligomers

Daniel H. Appella, Laurie A. Christianson, Isabella L. Karle et al. · Journal of the American Chemical Society · 1996 · 683 citations

Protein Assembly, Peptide Engineering, Altmetric Attention Score +19

Residue-based control of helix shape in β-peptide oligomers

Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein et al. · Nature · 1997 · 621 citations

Protein Assembly, Helix Shape, Natural Sciences +3