Basophils Play a Critical Role in the Development of IgE-Mediated Chronic Allergic Inflammation Independently of T Cells and Mast Cells

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

Life Sciences, Genetics, Immunology +14

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

Zhou Zhu, Robert Homer, Zhonde Wang et al. · Journal of Clinical Investigation · 1999 · 1.7K citations · Full text

Medicine, Immunology, Pathology +17

Association of Asthma with Serum IgE Levels and Skin-Test Reactivity to Allergens

B BURROWS, Fernando D. Martínez, Marilyn Halonen et al. · New England Journal of Medicine · 1989 · 1.7K citations

Life Sciences, Immunology, Allergy +10

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

William W. Busse, Jonathan Corren, Bobby Q. Lanier et al. · Journal of Allergy and Clinical Immunology · 2001 · 1.3K citations · Full text

Life Sciences, Immunology, Pharmacology +16

Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

Xiqing Cao, Elizabeth W. Shores, Jane Hu‐Li et al. · Immunity · 1995 · 1K citations · Full text

Life Sciences, Developmental Biology, Immunology +13