The role of Toll-like receptor-4 in pertussis vaccine-induced immunity

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.5K citations

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

Inflammation, Cytokine, Immunogenetics +11

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Kasper Hoebe, Xin Du, Philippe Georgel et al. · Nature · 2003 · 1.2K citations

Molecular Physiology, Signal Transduction, Natural Sciences +8

CD14 is required for MyD88-independent LPS signaling

Zhengfan Jiang, Philippe Georgel, Xin Du et al. · Nature Immunology · 2005 · 666 citations

Myd88-independent Lps, Signal Transduction, Signaling Pathway +6

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

Kasper Hoebe, Edith M. Janssen, Sung Ouk Kim et al. · Nature Immunology · 2003 · 445 citations

Systems Biology, Signal Transduction, Biochemistry +10