PubMed · 1984 · 108 citations · 10 references
PharmacyOncologyToxicologyCancer ControlCancer PreventionEnvironmental ToxicologyCancer MortalityCarcinogenicity AssessmentEnvironmental Cancer EpidemiologyOccupational Cancer PreventionOccupational CarcinogenesisRespiratory ToxicologyFormaldehyde ExposureIndoor Air CarcinogensMortality Experience AnalysisMortality Experience StudyOccupational Cancer ExposuresOccupational Inhalation Toxicology
To evaluate the potential carcinogenic effects of formaldehyde, we examined the proportionate mortality experience of embalmers licensed to practice in California. Mortality was significantly elevated for total cancer, arteriosclerotic heart disease, and suicide, whereas significant deficits were noted in mortality from diseases of the respiratory and genitourinary systems. Deaths from cancers of the brain, colon, and prostate and leukemia were significantly higher than expected. No increased mortality was seen for cancers of the respiratory tract, including the nasal passages, where an effect might be expected based on animal studies. A parallel mortality survey of embalmers from New York State showed similar findings, with excesses of brain tumors, leukemia, colon cancer, arteriosclerotic heart disease, and cirrhosis. Further investigation is needed to determine whether any of these outcomes is related to formaldehyde exposure.
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Mortality patterns among embalmers
Judy Walrath, Joseph F. Fraumeni · International Journal of Cancer · 1983 · 130 citations
Pharmacy, Oncology, Toxicology +17
Mortality study of pathologists and medical laboratory technicians.
J M Harrington, Henry Shannon · BMJ · 1975 · 126 citations · Full text