Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice

Identification and Importance of Brown Adipose Tissue in Adult Humans

Aaron M. Cypess, Sanaz Lehman, Gethin Williams et al. · New England Journal of Medicine · 2009 · 4.4K citations · Full text

Medicine, Nuclear Medicine, Radiology +15

Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

Alexandra C. McPherron, Ann M. Lawler, Se‐Jin Lee · Nature · 1997 · 4K citations

Life Sciences, Molecular Biology, Physiology +14

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Double muscling in cattle due to mutations in the myostatin gene

Alexandra C. McPherron, Se‐Jin Lee · Proceedings of the National Academy of Sciences · 1997 · 2K citations

Life Sciences, Genetics, Molecular Genetics +16

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Matthew D. Hirschey, Tadahiro Shimazu, Eric S. Goetzman et al. · Nature · 2010 · 1.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14