Knockout of the intermediate filament protein CP49 destabilises the lens fibre cell cytoskeleton and decreases lens optical quality, but does not induce cataract

Mice lacking vimentin develop and reproduce without an obvious phenotype

Emma Colucci‐Guyon, Marie‐Madeleine Portier, Irène Dunia et al. · Cell · 1994 · 607 citations

Life Sciences, Developmental Biology, Molecular Biology +9

Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice.

Hélène Baribault, J. E. Penner, Renato V. Iozzo et al. · Genes & Development · 1994 · 307 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates

Thomas M. Magin, Rolf Schröder, Sabine Leitgeb et al. · The Journal of Cell Biology · 1998 · 207 citations · Full text

Medicine, Cell Biology, Pathology +12

Autosomal-Dominant Congenital Cataract Associated with a Deletion Mutation in the Human Beaded Filament Protein Gene BFSP2

Petra Jakobs, John F. Hess, Paul G. Fitzgerald et al. · The American Journal of Human Genetics · 2000 · 179 citations · Full text

Medicine, Genetics, Molecular Genetics +14

Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality

Michael Hesse, Thomas Franz, Yoshitaka Tamai et al. · The EMBO Journal · 2000 · 167 citations · Full text

Life Sciences, Developmental Biology, Genetics +5