Concepedia

Istradefylline for Parkinson's disease patients experiencing motor fluctuations: Results of the KW-6002-US-018 study

Emmanuelle Pourcher, Hubert H. Fernandez, Mark Stacy, Akihisa Mori, Rocco Ballerini, Philip Chaikin

Parkinsonism & Related Disorders · 2011 · 117 citations · 10 references

DOI

Concepts

References

10

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

Andrew Hughes, S. E. Daniel, Linda Kilford et al. · Journal of Neurology Neurosurgery & Psychiatry · 1992 · 10.3K citations · Full text

D <sub>1</sub> and D <sub>2</sub> Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons

Charles R. Gerfen, Thomas M. Engber, Lawrence C. Mahan et al. · Science · 1990 · 2.9K citations

Adenosine A <sub>2A</sub> receptor antagonist istradefylline (KW‐6002) reduces “off” time in Parkinson's disease: A double‐blind, randomized, multicenter clinical trial (6002‐US‐005)

Peter A. LeWitt, Mark Guttman, James W. Tetrud et al. · Annals of Neurology · 2008 · 346 citations

Combined Use of the Adenosine A2A Antagonist KW-6002 with l-DOPA or with Selective D1 or D2 Dopamine Agonists Increases Antiparkinsonian Activity but Not Dyskinesia in MPTP-Treated Monkeys

Tomoyuki Kanda, Michael S. Jackson, Lance A. Smith et al. · Experimental Neurology · 2000 · 246 citations

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Placebo response in Parkinson's disease: Comparisons among 11 trials covering medical and surgical interventions

Christopher G. Goetz, Joanne Wuu, Michael P. McDermott et al. · Movement Disorders · 2008 · 242 citations

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