Concepedia

Combined Use of the Adenosine A2A Antagonist KW-6002 with l-DOPA or with Selective D1 or D2 Dopamine Agonists Increases Antiparkinsonian Activity but Not Dyskinesia in MPTP-Treated Monkeys

Tomoyuki Kanda, Michael S. Jackson, Lance A. Smith, R. K. B. Pearce, Joji Nakamura, Hiroshi Kase, Yoshihisa Kuwana, Peter Jenner

Experimental Neurology · 2000 · 246 citations · 32 references

DOI

Concepts

References

32

Biochemical pathophysiology of Parkinson's disease.

O Hornykiewicz, Stephen J. Kish · PubMed · 1987 · 852 citations

, , +6

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.

Robert F. Bruns, Gina H. Lu, Thomas A. Pugsley · Molecular Pharmacology · 1986 · 832 citations · Full text

Striatal Restricted Adenosine A<sub>2</sub> Receptor (RDC8) Is Expressed by Enkephalin but Not by Substance P Neurons: An In Situ Hybridization Histochemistry Study

Serge N. Schiffmann, O. E. Jacobs, Jean‐Jacques Vanderhaeghen · Journal of Neurochemistry · 1991 · 529 citations

Amantadine as treatment for dyskinesias and motor fluctuations in Parkinson's disease

Leonard Verhagen Metman, Paolo Del Dotto, Pepijn van den Munckhof et al. · Neurology · 1998 · 511 citations

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

John W. Daly, Pamela Butts-Lamb, William L. Padgett · Cellular and Molecular Neurobiology · 1983 · 443 citations · Full text

, , +11