Concepedia

Preclinical evaluation of the orally active camptothecin analog, RFS-2000 (9-nitro-20(S)-camptothecin) as a radiation enhancer

George P. Amorino, Sherri K. Hercules, Peter Mohr, Hongryull Pyo, Hak Choy

International Journal of Radiation Oncology*Biology*Physics · 2000 · 17 citations · 27 references

DOI

Concepts

References

27

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

Vilhelm A. Bohr · Cell · 1985 · 1.2K citations

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Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.

Y H Hsiang, M G Lihou, Leroy F. Liu · PubMed · 1989 · 1K citations

, , +17

Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity.

Christine Jaxel, Kurt W. Kohn, Mansukh C. Wani et al. · PubMed · 1989 · 450 citations

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X-Ray and Ultraviolet Sensitivity of Synchronized Chinese Hamster Cells at Various Stages of the Cell Cycle

Warren K. Sinclair, R. A. Morton · Biophysical Journal · 1965 · 302 citations · Full text

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Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome.

Gesine Fleischmann, Gert O. Pflugfelder, E K Steiner et al. · Proceedings of the National Academy of Sciences · 1984 · 227 citations · Full text

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