An efficient and reliable DNA extraction method for preimplantation genetic diagnosis: a comparison of allele drop out and amplification rates using different single cell lysis methods

Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification

Alan H. Handyside, E. Kontogianni, Kate Hardy et al. · Nature · 1990 · 1.6K citations

Fertility, Human Preimplantation Embryos, Genetics +16

Isothermal whole genome amplification from single and small numbers of cells: a new era for preimplantation genetic diagnosis of inherited disease

Alan H. Handyside, Mark D. Robinson, Robert J. Simpson et al. · Molecular Human Reproduction · 2004 · 241 citations · Full text

Genetic Testing, Reverse Genetics, Genetics +23

Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers.

Xiufang Cui, H H Li, Tushar M. Goradia et al. · Proceedings of the National Academy of Sciences · 1989 · 190 citations · Full text

Fertility, Single-sperm Typing, Genetics +20

Diagnosis and preventing inherited disease: Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis

I. Findlay, Pierre F. Ray, Philip Quirke et al. · Human Reproduction · 1995 · 174 citations

Proof of principle and first cases using preimplantation genetic haplotyping – a paradigm shift for embryo diagnosis

Pamela Renwick, Jane Trussler, Elham Ostad-Saffari et al. · Reproductive BioMedicine Online · 2006 · 152 citations

First Cases, Developmental Biology, Genetics +10