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Sophocarpine could decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, and might be selected as a promising agent for the clinical prevention and therapy of NASH.
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IKK-β links inflammation to obesity-induced insulin resistance
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Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
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