Structure-Based Ligand Discovery Targeting Orthosteric and Allosteric Pockets of Dopamine Receptors

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton, Louisa J. Bellis, A. Patrícia Bento et al. · Nucleic Acids Research · 2011 · 4.5K citations · Full text

Pharmacy, Bioinformatics, Chemical Biology +17

High-Resolution Crystal Structure of an Engineered Human β ₂ -Adrenergic G Protein–Coupled Receptor

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson et al. · Science · 2007 · 3.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Søren G. F. Rasmussen, Hee‐Jung Choi, Juan José Fung et al. · Nature · 2011 · 1.7K citations · Full text

Natural Sciences, Biochemistry, Biophysics +6

GPCR Engineering Yields High-Resolution Structural Insights into β ₂ -Adrenergic Receptor Function

Daniel M. Rosenbaum, Vadim Cherezov, Michael A. Hanson et al. · Science · 2007 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

Ellen Y. T. Chien, Wei Liu, Qiang Zhao et al. · Science · 2010 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17