Frequency of Driver Mutations in Lung Adenocarcinoma from Female Never-Smokers Varies with Histologic Subtypes and Age at Diagnosis - Concepedia

Concepedia

Publication | Closed Access

Frequency of Driver Mutations in Lung Adenocarcinoma from Female Never-Smokers Varies with Histologic Subtypes and Age at Diagnosis

169

Citations

37

References

2012

Year

Yang Zhang, Yihua Sun, Yunjian Pan, Chenguang Li, Lei Shen, Yuan Li, Xiaoyang Luo, Ting Ye, Rui Wang, Haichuan Hu,

Clinical Cancer Research

Abstract

The frequency of driver mutations in never-smoking female lung adenocarcinoma varies with histologic subtypes and age at diagnosis. These data have implications for both clinical trial design and therapeutic strategies.

References

	Year	Citations
Global cancer statistics Ahmedin Jemal, Freddie Bray CA A Cancer Journal for Clinicians	2011	55K
Global Cancer Statistics, 2002 Donald Maxwell Parkin, Freddie Bray, Jacques Ferlay, CA A Cancer Journal for Clinicians Epidemiology Of CancerWorldwide IncidenceCancer RegistrationCancer DeathCancer Risk Factors	2005	18.4K
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, New England Journal of Medicine	2004	11.4K
<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy J. Guillermo Paez, Pasi A. Jänne, Jeffrey C. Lee, Science	2004	9.4K
Mortality in relation to smoking: 40 years' observations on male British doctors Richard Doll, Richard Peto, Keith Wheatley, BMJ	1994	5.8K
Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer Eunice L. Kwak, Yung‐Jue Bang, D. Ross Camidge, New England Journal of Medicine	2010	4.5K
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib William Pao, Vincent A. Miller, Maureen F. Zakowski, Proceedings of the National Academy of Sciences	2004	4.3K
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma Keith T. Flaherty, Igor Puzanov, Kevin B. Kim, New England Journal of Medicine	2010	3.5K
Somatic mutations affect key pathways in lung adenocarcinoma Li Ding, Gad Getz, David A. Wheeler, Nature Somatic VariantSomatic MutationsBronchial NeoplasmCancer GeneticsSystems Biology	2008	2.7K
Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers Hisayuki Shigematsu, Tsuyoshi Takahashi, Masatoshi Nomura, JNCI Journal of the National Cancer Institute	2005	2.4K

Page 1